Dr. Urano's Blog

induced pluripotent stem cells

Soluble factors for regenerative medicine

We are looking for soluble factors in our body that can enhance the regeneration of damaged tissues in Wolfram syndrome and Type 1 diabetes. We have discovered two molecules so far. One of them is MANF.

We are trying to produce a large amount of these factors in the dish (recombinant proteins) and give these factors to animal models and cell models. We are also looking for methods/small molecules (i.e., drugs) to enhance the functions of these factors. This strategy is also related to “regenerative therapy”, but independent of stem cells.

Thank you for reading this. I hope you will have a wonderful Friday. Warmly, Fumi Urano