Dr. Urano's Blog

Molecular Pathways and Drug Targets

To identify drug targets for Wolfram syndrome, we have been analyzing molecular pathways altered in Wolfram syndrome patients. We have recently identified a calcium-dependent enzyme that is highly activated in Wolfram syndrome and discovered a drug that can reverse this process. The complete understanding of the pathway leading to the activation of this enzyme will provide us more drug targets, but we have one now. I will tell you more about this enzyme and a drug tomorrow.

Thank you for reading this.

Take care,

Fumi Urano