Dr. Urano's Blog

Glucose Meter

MANF, Wolfram, and Diabetes #6: Protecting remaining tissues

Yesterday, I articulated our strategy for protecting remaining beta cells and brain cells with MANF.

1. Inject recombinant MANF to patients.
2. Stabilize endogenous MANF< 3. Activate a receptor for MANF

I feel that these are realistic plans. The same strategy has been applied to GLP-1, a molecule produced in our guts, and GLP-1 related drugs are widely and successfully used for patients with type 2 diabetes.

<span style=”font-size: large;”><a href=”http://www.medscape.com/viewarticle/751632″><span style=”color: #3778cd;”>http://www.medscape.com/viewarticle/751632</span></a>

We are currently focusing on “recombinant” MANF, and hope to expand our research in this area.